Relaxium Sleep Review: An Evidence-Based Analysis of Natural Sleep Aid Ingredients

Introduction

In this article, The Sleep Syndicate will review Relaxium Sleep's ingredients and do our best to identify any scientific evidence that may identify the likelihood of those ingredients having an impact on your sleep quality. The goal is to help you make an informed decision about the effectiveness of sleep products available on the market. We don’t have partnerships with, or earn anything from, the products and solutions that we write about.

No material on this site or in this article is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking changes to health-related habits, and never disregard professional medical advice or delay in seeking it because of something you have read here.

What is Relaxium Sleep?

Relaxium Sleep is a supplement marketed as a natural solution for individuals struggling with sleep difficulties. The product claims to support better sleep quality through a blend of natural ingredients designed to promote relaxation and reduce night time awakenings.

Detailed Ingredient Analysis and Scientific Evidence

By presenting clinical research findings from scientific journals and articles, we aim to provide an unbiased overview of the ingredient's documented effects on sleep quality

1. Magnesium

Magnesium plays a critical role in neurological function and sleep regulation. Several peer-reviewed studies have explored its potential benefits:

• A study done by Wells, M. E., & Vaughn, B. V. (2012), Magnesium intake has been found to be inversely correlated to an increasing number of inflammation-related biomarkers, including plasma, and Protein C-reactive (CRP), a factor that may increase inflammatory stress which leads to disrupted sleep/sleep deprivation [1]
• According to the same study above, many illnesses that are classified as having a chronic inflammatory stress component have been linked to low magnesium levels. A modest magnesium deficit, which seems to be prevalent in humans, can worsen stress brought on by other variables, such as sleep deprivation or disturbed sleep, according to some findings in experimental studies. [1]
• A research done by Arab, A., Rafie, N., Amani, R. et al, found a correlation between magnesium status and sleep quality (daytime falling asleep, sleepiness, snoring, and sleep duration) based on observational studies. Although, well-designed randomized clinical trials with a bigger sample size and a longer follow-up period (greater than 12 weeks) are necessary to better elucidate the relationship between dietary magnesium and sleep patterns. [2]

In summary, a magnesium deficit, if you have one, may indirectly contribute to lower sleep quality.  The verdict is that there is some evidence that ensuring you have sufficient magnesium can be a factor in sleep quality.

2. Valerian Root

Valerian root has been traditionally used as a sleep aid, with scientific evidence and support:

• A study by the European Medicines Agency, E.H. (2015) suggests that Although the EMA monograph lists gastrointestinal symptoms (such as nausea and cramping in the abdomen) as undesired effects, Valerian is thought to be rather harmless and easily tolerated. The components that contribute to the effectiveness of valerian root hydroalcoholic extracts are unknown, despite the fact that they were shown to increase sleep latency and quality when taken as directed. [3]
• According to this study, valerian can serve as a safe and effective herb for addressing anxiety, insomnia, and related comorbidities both on its own and in combination with other similar herbal and medicinal ingredients. One question that comes up for further research is if valerian is particularly successful in addressing sleep problems where anxiety levels are higher. Indeed, the finding that children with hyperactivity experienced the greatest decrease in sleep issues from Valerian may indicate that Valerian is more beneficial in treating sleeplessness linked to specific illnesses like anxiety. [4]

In conclusion, valerian root seems to have some evidence of a positive effect on some aspects of sleep quality, but may have some undesirable side effects. Of note, with any herbal extracts or ingredients, there can be a wide range in the dosage depending on packaging. A more thorough investigation into dosage and what chemical compound(s) within valerian root have an impact on sleep is needed. 

3. Melatonin

Melatonin is a hormone naturally produced by the pineal gland, crucial for sleep-wake cycle regulation:

• Dietary melatonin intake was linked to lower mortality, cardiovascular, and overall risks in Japanese adults, according to the study. This study found in the American Journal of Epidemiology suggests that melatonin may contribute to overall improvements in life quality. [5]
• According to Dawson, D., & Encel, N. (1993), One of melatonin's functions in humans is to transduce the light-dark cycle and establish a window of opportunity that increases the likelihood of falling asleep. Because circulating melatonin levels are low, melatonin is therefore likely to be an effective therapeutic substance for sleep disruption linked to increased temperature. Melatonin's properties point to a potential benefit in the treatment of sleep disorders including irregular waking and sleep cycles. [6]
• A study done by Cardinali, D. P., & Garay, A. (2023) found out that since melatonin intake is not patented and has not been scientifically demonstrated to be helpful, the pharmaceutical industry and even the FDA are not driven to promote its usage. However, the pharmaceutical sector may look into the potential for melatonin to be used in conjunction with other drugs to achieve therapeutic benefits. Melatonin would be especially beneficial because of its low cost, low toxicity, and oral availability. [7]

Surprisingly, there is not a lot of peer-reviewed scientific evidence for the use of melatonin in improving sleep quality, especially given the popularity of this compound.  There is evidence that melatonin plays a role in circadian sleep cycles in humans, but the lack of attention to melatonin by the pharmaceutical industry as a potential treatment, in a very large and lucrative sleep aid market is perhaps telling. 

Potential Side Effects and Considerations

While Relaxium Sleep contains natural ingredients, potential side effects of these ingredients have been identified to include:

• Mild drowsiness
• Potential interactions with existing medications
• Individual variability in response

Individuals with pre-existing medical conditions or those taking prescription medications should consult healthcare professionals before starting any new supplement regimen. [8]

Scientific Limitations and Research Gaps

It's essential to recognize that while individual ingredients show promise, comprehensive, independent research specifically on Relaxium Sleep's proprietary blend seems to be lacking and should be encouraged.

Beyond Supplements: Holistic Sleep Improvement

While Relaxium Sleep might offer temporary support for some, sustainable sleep improvement should include a holistic approach:

• Consistent sleep schedule
• Sleep hygiene optimization
• Regular physical activity
• Balanced nutrition
   

A Science-Backed Alternative

At The Sleep Syndicate, we've developed a 6-week program that goes beyond temporary solutions. Our science-based approach guides you through gradual, scientifically-backed changes to your sleeping patterns by applying tried-and-tested behavior modification strategies.  

Discover Our 6-Weeks to Better Sleep Program 

Citations

[1] Wells, M. E., & Vaughn, B. V. (2012). Poor Sleep Challenging the Health of a Nation. The Neurodiagnostic Journal, 52(3), 233–249. https://doi.org/10.1080/21646821.2012.11079859

[2] Arab, A., Rafie, N., Amani, R. et al. The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature. Biol Trace Elem Res 201, 121–128 (2023). https://doi.org/10.1007/s12011-022-03162-1

[3] European Medicines Agency, E. H. (2015). European Union herbal monograph on Valeriana officinalis L., radix.

[4] Shinjyo N, Waddell G, Green J. Valerian Root in Treating Sleep Problems and Associated Disorders—A Systematic Review and Meta-Analysis. Journal of Evidence-Based Integrative Medicine. 2020;25. doi:10.1177/2515690X20967323

[5] Chisato Nagata, Keiko Wada, Michiyo Yamakawa, Yuma Nakashima, Sachi Koda, Takahiro Uji, Sakiko Onuma, Shino Oba, Yusuke Maruyama, Atsuhiko Hattori, Associations Between Dietary Melatonin Intake and Total and Cause-Specific Mortality Among Japanese Adults in the Takayama Study, American Journal of Epidemiology, Volume 190, Issue 12, December 2021, Pages 2639–2646, https://doi.org/10.1093/aje/kwab213

[6] Dawson, D., & Encel, N. (1993). Melatonin and sleep in humans. Journal of Pineal Research, 15(1), 1–12. https://doi.org/10.1111/j.1600-079x.1993.tb00503.x

[7] Cardinali, D. P., & Garay, A. (2023). Melatonin as a Chronobiotic/Cytoprotective Agent in REM Sleep Behavior Disorder. Brain Sciences, 13(5), 797. https://doi.org/10.3390/brainsci13050797

[8] https://www.nccih.nih.gov/health/melatonin-what-you-need-to-know

Disclaimer

THIS WEBSITE AND PROGRAM DOES NOT PROVIDE MEDICAL ADVICE AND IS NOT INTENDED TO ADDRESS MEDICAL CONDITIONS 

No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking changes to health-related habits, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.